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MikeLaRonde



Joined: 11 Jun 2001
Posts: 768

PostPosted: Sun Oct 09, 2022 9:13 am    Post subject: Reply with quote

The answer to your question is at the end of this video interview, which provides an insight into his late life. Love him or hate him, this short is totally worth watching ... the visiting interviewer is a bit condescending .. video quality is excellent.
https://bradabrahams.net/dyswis

To me the timing of his death seems suspicious, but let's just say the GB-4000 probably doesn't work.

For the true fans who might be reading this, a much longer, better and more in character interview, touching all every possible "conspiratorial" subject, is here:
https://www.bitchute.com/video/RYtnXQhOadrV/

David was definitely not a hater. Calling out evil people is not the same as hating. According to Rense, one of his later gigs was playing music for patients in hospice.

Trying to find an example only comes up with this from 30+ years ago ... last song is ok, the rest are terrible.
https://www.youtube.com/watch?v=xREh7MOgFAA

Thanks to Jeff Rense for keeping his work alive. Here's a great collection
https://www.renseradio.com/ddees-gallery/

Here's Jeff's tribute page
https://www.renseradio.com/ddees-tribute/
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mac



Joined: 07 Mar 1999
Posts: 17744
Location: Berkeley, California

PostPosted: Tue Jan 03, 2023 12:36 pm    Post subject: Reply with quote

There's a bunch of nutty stuff being posted by marmalade, Bard, and techno claiming that vaccination is not just not working but causing the mutations in the COVID virus. Techno posted a WSJ article claiming that Biden is not prioritizing treatment and that is making things worse. While there are any number of legitimate areas of inquiry about what the path of COVID on human health might be, whether it will follow the path of the Spanish Flu and become endemic but less deadly, whether we should be doing more research on treatment, and whether RNA-based vaccines are as effective, you're not going to find either information or reasoned discussion on bitchute or the other sources used by the tin foil hat boys. It is clear that viruses mutate within a human body, and that the longer an infection lasts the greater the chance for such mutations. The idea that such mutation is as worrisome in the vaccinated is less likely. While it is true that a vaccine doesn't instantly kill the virus, it does rev up the immune system and prevent the lengthy infections that increase the rate of mutation, and they prevent the development of substantial viral loads that increase transmission. Here's a readable article on COVID mutation.

Quote:
coronoavirus mutating into another version
How COVID-19 mutates and how it affects vaccines
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Viruses are constantly changing. Their genetic code is prone to changes called mutations that can change how a virus looks or affects its hosts.

“Words like mutation make people think that something terribly wrong is occurring or something is dramatically different,” said Douglas Kasper, MD. Dr. Kasper is the section head of infectious disease at the University of Illinois College of Medicine Peoria and a leader in the OSF HealthCare response to COVID-19.

But often that’s not the case. Viral mutations typically have no significant immediate effect on the ability of the virus to cause disease in humans.

Dr. Kasper explains how viruses mutate into variants and strains.

How viruses mutate
versions of a coronavirusViruses rely on a host to survive and replicate. They invade the body of a human or an animal and bind with the host’s cells to allow their own genetic material (RNA) to enter the cells. The host’s own cells read the genetic code and replicate it, making more of the virus.

That new virus then leaves the cell in search of another host to infect.

Sometimes when that genetic code is being translated into proteins, a piece of the code gets changed. This is called a mutation, and they happen frequently.

“Human cells are DNA-based. And DNA – thankfully for us – has much better integrity than RNA. DNA has the ability to check itself. If there are small changes, or what we call mutations, to its genetic code, it can fix itself and get back to normal. RNA is a lot more messy,” Dr. Kasper said.

“This perpetual cycle goes on of constant replication. Each time a replication occurs, there is a small chance that code could change. When you have this go over a huge population over time, the odds start to favor that the virus will adjust. It’s evolution on a very, very rapid level.”

So it’s not surprising that a virus like SARS-CoV-2, the virus that causes COVID-19, would mutate. That’s something scientists and vaccine developers have expected since the beginning of the current epidemic.

The question is how drastically and quickly is the virus changing.

Drift vs. shift
“Most of the time when these mutations occur, they are of no consequence, because one adjustment doesn’t change the protein configuration,” Dr. Kasper said.

These small changes are called “drift,” and usually translate into changes in a protein’s structure that allow our immune systems to continue to recognize and respond to an antigen.

What’s more concerning are changes called “shift” – abrupt, major changes in the structure of a virus.

If a virus changes enough, it could respond differently to treatments or become less recognizable to the antibodies developed after natural infection or vaccination. Scientists around the world work closely to determine if the multiple variants we’ve seen emerge impact vaccine effectiveness and therapeutic treatment options.

In some cases, it’s possible that a variant could lead to worse illness or clinical outcomes. Fortunately, the available vaccines remain highly effective against protecting for serious clinical outcomes associated with COVID-19 infection, making timely vaccination (including booster) even more of a priority for communities.

There will likely continue to be variant strains that will be watched by worldwide health leaders. The key point remains ensuring that ongoing vaccination provides adequate protection from variant SARS CoV2 strains.

Effectiveness against variant strains
Vaccine developers are well aware of the ability of viruses to change over time, and they created vaccines that would account for that.

Because SARS-CoV-2 is part of a large group of coronaviruses, researchers have seen many variations of the spike proteins for which these viruses are named. When developers created vaccines against COVID-19, they tested them against many different variations of the spike protein.

Research shows the antibodies created after vaccination will recognize and respond to many variations of the spike protein. This leads experts to be fairly confident the vaccines will continue to be effective against many mutations that may arise.

But they also prepared for how they would respond if a dramatic shift occurs.

About the vaccines
The Pfizer and Moderna vaccines both use mRNA to teach our bodies to recognize and fight off these spike proteins.

While they have multiple ingredients, mRNA vaccines have essentially two important components:

mRNA, or a small piece of the virus’s genetic code
A “vessel” of salt, fat and sugar that delivers the mRNA to our cells
If this structure of the spike protein changed enough that the vaccine’s effectiveness was compromised, it’s likely only that small piece of genetic code would need to be updated – which is much simpler than developing an entirely new vaccine.

“Part of the reason the mRNA structure was chosen was because of its ability to address these kinds of changes. It was always likely that there would need to be an adjustment,” Dr. Kasper said.

Data shows the vaccines provide “protection against several emerging variants.”

“There’s always been an expectation that over time, if these spike proteins do change significantly, the vaccines could be updated to address the changes and still provide the benefit to society that it’s intended to,” Dr. Kasper said.
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MalibuGuru



Joined: 11 Nov 1993
Posts: 9293

PostPosted: Tue Jan 03, 2023 1:10 pm    Post subject: Reply with quote

https://open.substack.com/pub/alexberenson/p/something-wicked-this-way-comes-and?utm_source=share&utm_medium=android
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mac



Joined: 07 Mar 1999
Posts: 17744
Location: Berkeley, California

PostPosted: Tue Jan 03, 2023 1:46 pm    Post subject: Reply with quote

MalibuGuru wrote:
https://open.substack.com/pub/alexberenson/p/something-wicked-this-way-comes-and?utm_source=share&utm_medium=android


Like I said, trolling for paranoid theories among the “pandemic’s wrongest man” will not help you learn or think. But it will make Alex money.

https://www.theatlantic.com/ideas/archive/2021/04/pandemics-wrongest-man/618475/
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techno900



Joined: 28 Mar 2001
Posts: 4161

PostPosted: Tue Jan 03, 2023 2:47 pm    Post subject: Reply with quote

Anyone dumb enough to think the science surrounding Covid and vaccinations is settled is hopeless.

Mac's one year old posted paper on covid mutating doesn't address the more current findings. To assume that Douglas Kasper, MD. has it absolutely right is foolish. It will likely take several more years to figure this thing out, so in the meantime, keeping an open mind is a logical conclusion, at least for some of us.


Last edited by techno900 on Wed Jan 04, 2023 9:32 am; edited 1 time in total
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mac



Joined: 07 Mar 1999
Posts: 17744
Location: Berkeley, California

PostPosted: Tue Jan 03, 2023 8:24 pm    Post subject: Reply with quote

techno900 wrote:
Anyone dumb enough to think the science surround Covid and vaccinations is settled is hopeless.

Mac's one year old posted paper on covid mutating doesn't address the more current findings. To assume that Douglas Kasper, MD. has it absolutely right is foolish. It will likely take several more years to figure this thing out, so in the meantime, keeping an open mind is a logical conclusion, at least for some of us.


Don’t put words in my mouth fool. I didn’t suggest that the science is settled, I identified at least three issues that could be discussed. Quickly followed by a paranoid post from the dumbest man in Malibu. Do you have anything constructive to post that might actually be on point and based on science—not on selling books to the haters?
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MikeLaRonde



Joined: 11 Jun 2001
Posts: 768

PostPosted: Wed Jan 04, 2023 12:07 am    Post subject: Reply with quote

zap

Last edited by MikeLaRonde on Fri Feb 17, 2023 11:36 pm; edited 2 times in total
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mac



Joined: 07 Mar 1999
Posts: 17744
Location: Berkeley, California

PostPosted: Wed Jan 04, 2023 1:05 am    Post subject: Reply with quote

Can’t fix crazy. But then there are facts. On the question of are mrna vaccines as good? Only when actually studied. By scientists.

Quote:
mRNA vaccine-induced antibodies more effective than natural immunity in neutralizing SARS-CoV-2 and its high affinity variants

Yunkai Yu 1 , Dominic Esposito 2 , Zhigang Kang 1 , Jianming Lu 3 , Alan T Remaley 4 , Valeria De Giorgi 5 , Leonard N Chen 5 , Kamille West 5 , Liang Cao 6
Affiliations expand
PMID: 35173254 PMCID: PMC8850441 DOI: 10.1038/s41598-022-06629-2
Free PMC article
Abstract

Several variants of SARS-CoV-2 have emerged. Those with mutations in the angiotensin-converting enzyme (ACE2) receptor binding domain (RBD) are associated with increased transmission and severity. In this study, we developed both antibody quantification and functional neutralization assays. Analyses of both COVID-19 convalescent and diagnostic cohorts strongly support the use of RBD antibody levels as an excellent surrogate to biochemical neutralization activities. Data further revealed that the samples from mRNA vaccinated individuals had a median of 17 times higher RBD antibody levels and a similar degree of increased neutralization activities against RBD-ACE2 binding than those from natural infections. Our data showed that N501Y RBD had fivefold higher ACE2 binding than the original variant. While some antisera from naturally infected subjects had substantially reduced neutralization ability against N501Y RBD, all blood samples from vaccinated individuals were highly effective in neutralizing it. Thus, our data indicates that mRNA vaccination may generate more neutralizing RBD antibodies than natural immunity. It further suggests a potential need to maintain high RBD antibody levels to control the more infectious


Seventeen times higher.
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techno900



Joined: 28 Mar 2001
Posts: 4161

PostPosted: Wed Jan 04, 2023 9:50 am    Post subject: Reply with quote

From the study Mac posted:

Quote:
The clinical validation study of the test was performed using 41 serum samples from 33 convalescent donors (Supplementary Table 1) with documented history of COVID-19 prior to September 1, 2020, months prior to the first reported alpha variant which contains RBD mutation N501Y and from 171 healthy donors collected before January 2020

How relevant is this, given the number of new variants around today?[/quote]
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mac



Joined: 07 Mar 1999
Posts: 17744
Location: Berkeley, California

PostPosted: Wed Jan 04, 2023 10:29 am    Post subject: Reply with quote

techno900 wrote:
From the study Mac posted:

Quote:
The clinical validation study of the test was performed using 41 serum samples from 33 convalescent donors (Supplementary Table 1) with documented history of COVID-19 prior to September 1, 2020, months prior to the first reported alpha variant which contains RBD mutation N501Y and from 171 healthy donors collected before January 2020

How relevant is this, given the number of new variants around today?
[/quote]

Oh look, a troll has moved the goal posts again. Yes, there is a new variant. And? Do you have any actual studies that conclude how this variant formed and spread?

Research is always going to trail what is actually happening. What is relevant about the study that I posted is that it showed that immunity conferred by mrna vaccines was more robust than that conferred by infection. Seventeen times more robust. I guess techno missed that, searching for confirmation bias. Sheesh.
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